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Publications

1. Bacterial beta-lactamase fragment complementation strategy can be used as a method for identifying interacting protein pairs
   
   PARK, JONG-HWA, JUNG HO BACK, SOO HYUN HAHM, HYE-YOUNG SHIM, MIN JU PARK,SUNG IL KO, AND YE SUN HAN,
   J. Microbiol. Biotechnol., 17:1607-1615, 2007   



2. Genistein-induced apoptosis of human breast cancer MCF-7 cells involves calpain-caspase and spoptosis signaling kinase1-p38 mitogen-activated protein kinase activation cascades
   
   Hye-Young Shim, Jong-Hwa Park, Hyun-Dong Paik, Seung-Yeol Nah,Darrick S.H.L. Kim and Ye Sun Han,
   Anti-cancer drugs, 18:649-657, 2007   



3. Acacetin-induced apoptosis of human breast cancer MCF-7 cells involves caspase cascade, mitochondria-mediated death signaling and SAPK/JNK1/2-c-Jun activation
   
   Hye-Young Shim†, Jong-Hwa Park, Hyun-Dong Paik, Seung-Yeol Nah, Darrick S.H.L. Kim, and Ye Sun Han,
   Molecules and cells, 24:95-104, 2007   



4. Alzhemer's disease drug discovery from Herbs: Neuroprotectivity from beta-amyloid (1-42) insult
   
   DARRICK S.H.L. KIM, JIN-YUNG KIM, and YE SUN HAN.,
   THE JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDIC, 13:333-340, 2007   



5. Human glycine alpha1 receptor inhibition by quercetin is abolished or inversed by alpha267 mutations in transmembrane domain 2
   
   Byung-Hwan Lee, Jun-Ho Lee, In-Soo Yoon, Joon-Hee Lee, Sun-Hye Choi,Ye Sun Han, Hyun-Dong Paik, Ssang-Goo Cho,,
   Brain research, 1161:1-10, 2007   



6. Induction of apoptotic cell death by synthetic naringenin derivatives in human lung epithelial carcinoma A549 cells
   
   Eung-Ryoung LEE,Yong-Jin KANG,Hye-Yeon CHOI,Geun-Ho KANG,Jung-Hyun KIM,Bong-Woo KIM,Ye Sun HAN,Seung-Yeol NAH,Hyun-Dong PAIK,Yong-Sun PARKand Ssang-Goo Cho,
   Biol. Pharm. Bull., 31:2394, 2007   



7. A versatile endonuclease IV from Thermus thermophilus has uracil-excising and 3'-5' exonucease activity
   
   Jung Ho Back, Ji Hyung Chung, Jong Hwa Park, Ye Sun Han,
   BBRC, 346:889-895, 2006   



8. A disticnt TthMutY bifunctional glycosylase that hydrolyses not only adenine but also thymine apposite 8-oxoguanine in the hyperthermaophilic bacterium, Thermus thermophilus
   
   Jung Ho Back, Jong Hwa Park, Ji Hyung Chung, Darrick S.H. L. Kim, Ye Sun Han,
   DNA repair, 5:894-903, 2006   



9. T-type calcium channel trigger p21ras signaling pathway to ERK in Cav3.1-expressed HEK293 cells
   
   Juhyun Choi, Jong-Hwa Park, Oh Yeun Kwon, Sunoh Kim, Ji Hyung Chung,Dae Sik Lim, Key Sun Kim, Hyewhon Rhim, Ye Sun Han,
   Brain Research, 1054:22-29, 2005   



10. The biochemical activation of T-type Ca2 channels in HEK293 cells stably expressing α1G and Kir2.1 subunits
    
    The biochemical activation of T-type Ca2+ channels in HEK293 cells stably expressing α1G and Kir2.1 subunits, Taehyun Kim, Juhyun Choi, Sunoh Kim, Ohyeun Kwon, Seung-Yeol Nah, Hyewhon Rhim, Ye Sun Han,
    BBRC, 324:401-408, 2004   



11. Construction of Bacterial Artificial Chromosome Library from Electrochemical Microorganisms
    
    Jung Ho Back, Man Su Kim,Hyuk Cho, In Seop Chang, Jiyoung Lee, Kyung Sik Kim, Byung Hong Kim, Young In Park and Ye Sun Han,
    FEMS letter, 238:65-70, 2004   



12. Enhancement of lipase activity from Acinetobacter Species SY-01 by random mutagenesis and the role of lipase-specific chaperone
    
    Soo-Jin Han, Ji Hyung Chung, Chan Seong Cheong, Il Yup Chung, Ye Sun Han,
    Enzyme & Microbial Technology, 35:377-384, 2004   



13. Endonuclease IV Enhances Base Excision Repair of endonuclease III from Methanobacterium thermoautotrophicum
    
    Jung Ho Back, Ji Hyung Chung, Young In Park , Key-Sun Kim and Ye Sun Han,
    DNA repair, 2:455-470, 2003   



14. Association of Hepatitis B Virus Polymerase with PML Nuclear Bodies Mediated by the S100 Family Protein p11
    
    Juhyun Choi, Dae-Sik Lim, Byung-Yoon Ahn,Young In Park and Ye Sun Han,
    BBRC, 305:1049-1056, 2003   



15. Molecular Cloning and Characterization of a Novel NADPH Quinone Oxidoreductase from Kluyveromyces Marxianus
    
    Wook Hyun Kim, Jung Ho Back, Ji Hyung Chung, Juhyun Choi, Joo Hwan Cha, Hun Yeoung Koh and Ye Sun Han,
    JBMB, 36:442-449, 2003   



16. Expression and Characterization of a Novel Enantioselective Lipase from Acinetobacter species SY-012
    
    Soo-Jin Han, Jung Ho Back, Moon Young Yoon, Pyong Kyun Shin, Chan Seong Cheong, Moon-Hee Sung, Seung-Pyo Hong, Il Yup Chung, Ye Sun Han,
    Biochimie, 85:501-510, 2003   



17. Stereochemical control in diastereoselective reduction of -substituted--ketoesters using a reductase purified from kluyveromyces marxianus.
    
    Joo Hwan Cha, Ae Nim Pae, Kyung Il Choi, Yong Seo Cho, Wook Hyun Kim, Ye Sun Han, Hong-Chul Yun, Jongsoo Lee, Hun Yeong Koh,
    Biotechnology Letters, 24:1695-1698, 2002   



18. Thermostable Hydantoinases from hyperthermophilic archaeon, Methanococcus jannaschii
    
    Ji Hyung Chung, Jae-Hwan Lim, Young In Park and Ye Sun Han,
    Enzyme & Microbial Technology, 30:867-874, 2002   



19. Expression of the Active Human and Duck Hepatitis B Virus Polymerases in Heterologous system of Pichia methanolica
    
    Juhyun Choi, Eunice E. Kim, Young In Park, and Ye Sun Han,
    Antiviral research, 55:279-290, 2002   



20. Mutational effects on thermostable superoxide dismutatse from Aquifex pyrophilus: Understanding the molecular basis of protein thermostability
    
    Jae-Hwan Lim, Kwang Yeon Hwang, Juhyun Choi, Byung-Yoon Ahn, Yunje Cho and Ye Sun Han,
    BBRC, 288:263-268, 2001   



21. Repair Activities of 8-Oxoguanine DNA Glycosylase from Archaeoglobus fulgidus, a Hyperthermophilic Archaeon
    
    Ji Hyung Chung, Moo-Jin Suh, Young In Park, John A. Tainer and Ye Sun Han,
    Mutation Research, 486:99-111, 2001   



22. Biochemical characterization of a novel hypoxanthine/xanthine dNTP pyrophosphatase from Methanococcus jannaschii
    
    Ji Hyung Chung, Jung Ho Back, Young In Park and Ye Sun Han,
    Nucleic Acids Research, 29:3099-3107, 2001   



23. Molecular cloning and characterization of thermostable DNA ligase from Aquifex pyrophilus, a hyperthermophilic bacterium
    
    Jae-Hwan Lim, Juhyun Choi, Su-Jin Han, Sung Hou Kim, Hye-Zin Hwang, Dong-Kyu Jin, Byung-Yoon Ahn and Ye Sun Han,
    Extremophiles, 5:161-168, 2001   



24. Mutational analyses of Aquifex pyrophilus DNA ligase Define Essential Domains for Self-adenylation and DNA binding activity
    
    Jae-Hwan Lim, Juhyun Choi, Wookhyun Kim , Byung-Yoon Ahn and Ye Sun Han,
    Archives Biochem. Biophysics, 388:253-260, 2001   



25. Structural basis for cold adaptation Sequence, biochemial properties and Crystal structure ofmalate dehydrogenase from a psychrophile Aquasprillium arcticum
    
    S. Y. Kim, K. Y. Hwang, Y. S. Han and Y. Cho,
    J. Biol. Chem, 274:11761-11767, 1999   



26. Random sequence analysis of the genomic DNA of Methanopyrus kandleri and Molecular cloning of the gene encoding a homologue of the catalytic subunit of carbon monoxidedehydrogenase
    
    H.-S. Shin, J.-R. Ryu, Y. S. Han, Y.-J. Choi and Y.G. Yu, J.,
    J. Microbiol. Biotechnol., 9:404-413, 1999   



27. Structure-based identification ofthe biochemical function of a hypothetical protein fromMethanococcus jannashii: MJ0226
    
    K. Y. Hwang, J. H. Chung, S-H.Kim., Y. S. Han and Y. Cho.,
    Nature Structural Biology, 6691-6696:, 1999   



28. Cloning, Expression of Superoxide Dismutase from Aquifex pyrophilus, A HyperthermophilicBacteria
    
    Jae-Hwan Lim, Yeon Gyu Yu, In-Geol Choi, Jae-Ryeon Ryu, Byung-Yoon Ahn, Sung-Hou Kim and Ye Sun Han,
    FEBS letter, 406:142-146, 1997 



29. Crystal Structure of an Fe-Superoxide Dismutase from the hyperthermophile Aquifex Pyrophilus at 1.9 A Resolution: structural Basis for thermostability
    
    Jae-Hwan Rhim, Yeon Gyu Yu, Ye Sun Han, Seung-Je Cho, Byungyun Ahn, Sung-Hou Kim and Yunje Cho,
    J. of Molecular Biology, 270:259-274, 1997 



30. Random sequence analysis of genomic DNA of a hyperthermophile: Aquifex pyropyilus
    
    In-Geol Choi, Sang Suk Kim, Jae-Ryeon Ryu, Ye Sun Han, Won-Gi Bang, Sung-Hou Kim and Yeon Gyu Yu,
    Extremophiles, 1:125-134, 1997 



31. Analysis of phosphopeptides by capillary electrophoresis and matrix assisted laser desorption ionization-time of flight mass spectrometry
    
    Young Sook Yoo, Ye Sun Han, Moo Jin Suh and Jongsei Park,
    J. of Chrom, 763:285-293, 1997   



32. Molecular Analysis using High Performance Capillary Electrophoresis
    
    Yoo, Y. S., Ban, E. M., Kim, Ye Sun Han., Park, J.,
    Anal. Sci. & Tech., 8:881-886, 1995 



33. 2D 1H and 31P NMR Spectra and Disorted A-DNA-Like Duplex Structure of a phosphorodithioate Oligonucleotide
    
    Ye Sun Han, Zhu, F. C., Luxon, B. A., Gorenstein, D. G.,
    J. Biomol. Struct. Dyn., 11:685-702, 1993 



34. DNA - The Ultimate phosphorus Polymer: 31P One- and Two- Dimensional NMR Spectroscopy of Oligonucleotides and Protein - DNA Complexes, Gorenstein
    
    D. G., Karslake, C., Granger, J. N., Ye Sun Han, Piotto, M. E.,
    ACS symposium Seires No. 486, Phosphorous Chemistry : Developments in American Science, Chapter 16:202-217, 1992 



35. Synthesis, NMR and Structure of Oligonucleotide Phosphorodithioates
    
    Piotto, M. E., Granger, J. A., Ye Sun Han, Farschtshi, N. Gorenstein, D. G.,
    Tetrahedon, 47:2449-2461, 1991 



36. 1H 2D NMR of the Oligonucleotide Phosphorodithioate d(CGCTpS2-TpS2-AAGCG). An Unusual Hairpin Loop Structure, Piotto
    
    M. E., Granger, J. N., Ye Sun Han, Gorenstein, D. G.,
    J. Am. Chem. Soc., 112:8632-8634, 1990 



37. Genistein-induced apoptosis of human breast cnacer MCF-7 cells involves calpain-caspase and spoptosis signaling kinase 1-p38 mitogen-activated protein kinase activation cascades
    
    Hye-Young Shim, Jong-Hwa Park, Hyun-Dong Paik, Seung-Yeol Nah,Darrick S.H.L. Kim and Ye Sun Han,
    Anti-cancer drugs, 18:649-657, 007   

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